Mice

129-E Mouse

NOTE: The E indicates that this animal’s health status meets our VAF/Elite™ profile. For additional information, please check out the VAF/Elite™ definition: http://www.criver.com/files/pdfs/rms/rm_rm_r_vaf_profiles.aspx Origin Developed by Dr. L.C. Stevens from The Jackson Laboratory. During the 1970s, Dr. Stevens introduced this line to ... more

11BHSD2 Mouse

Origin The 11BHSD2 mouse was produced by injection of a construct, containing 11β-HSD2 cDNA isolated from mouse kidney and cloned into plasmid Clone 26 to recruit the 5.4 kb mouse α–myosin heavy chain (α-MHC) promoter, into pronuclei of C57BL/6 embryos. ... more

JAX

Mice bred in The Jackson Laboratory may be ordered on demand. Please, contact us at info@velaz.cz. That includes these strains: ApoE http://www.criver.com/products-services/basic-research/find-a-model/jax-mice-strain-apoe-knockout B6CBAF1/J http://www.criver.com/products-services/basic-research/find-a-model/jax-mice-strain-b6cbaf1-j B6D2F1/J http://www.criver.com/products-services/basic-research/find-a-model/jax-mice-strain-b6d2f1-j BALB/cJ http://www.criver.com/products-services/basic-research/find-a-model/jax-balbcj BALB/cByJ http://www.criver.com/products-services/basic-research/find-a-model/jax-mice-strain-balb-cbyj C3H/HeOuJ http://www.criver.com/products-services/basic-research/find-a-model/jax-c3h-mouse C57BL/6J http://www.criver.com/products-services/basic-research/find-a-model/jax-mice-strain-c57bl-6j CBA/J http://www.criver.com/products-services/basic-research/find-a-model/jax-mice-strain-cba- DBA/1J http://www.criver.com/products-services/basic-research/find-a-model/jax-mice-strain-dba-1j DBA/2J http://www.criver.com/products-services/basic-research/find-a-model/jax-mice-strain-dba-2j db/db http://www.criver.com/products-services/basic-research/find-a-model/jax-mice-strain-diabetic-mice-db-db NOD http://www.criver.com/products-services/basic-research/find-a-model/jax-mice-strain-nod-mice NOD ... more

NMRI

Origin Swiss-type mouse, which Clara Lynch gave to Poiley in 1937. He maintained an inbred line of this animal until the 51st generation, before he transferred it to the Naval Medical Research Institute. Introduced into Charles River Laboratories in 1979 ... more

Athymic Nude Mice

Origin This immunodeficient nude mouse originated from NIH and was originally thought to be a BALB/c congenic. It was later determined that it was not inbred and is therefore maintained as an outbred. It is not associated with any stock or ... more

SHC Mice

Origin The hairless SCID congenic was created in 2009 by Charles River Research Models by using marker-assisted accelerated backcrossing to place the hairless gene (Hrhr) present in the Crl:SKH1-Hrhr stock onto a CB17/Icr-Prkdcscid/IcrIcoCr genetic background. These mice are homozygous for both Hrhr and Prkdcscid mutations, ... more

NU/NU Mouse

Origin This immunodeficient nude mouse originated from NIH and was originally thought to be a BALB/c congenic. It was later determined that it was not inbred and is, therefore, maintained as an outbred and is not associated with any stock ... more

NIH-III Mouse

Origin Most commonly called the NIH-III, it was developed at NIH. In addition to the nude gene, which results in the absence of thymus and T-cell function, this mouse has two other mutations important in regulating the function of the ... more

SCID Beige mice

Origin A congenic mouse that possesses both autosomal recessive mutations SCID (Prkdcscid) and beige (Lystbg-J). The SCID mutation results in severe combined immunodeficiency affecting both the B and T lymphocytes. The beige mutation results in defective natural killer (NK) cells. ... more

SHO mice

Origin The hairless SCID mouse was produced by Charles River Research Models in 2007 by inter-crossing the Crl:HA-Prkdcscid and Crl:SKH1-Hrhr stocks. The resulting animals are homozyogous for the Prkdcscid and theHrhr mutations and thus exhibit the severe combined immunodeficiency phenotype characteristic of SCID mice and ... more

SCID mice

Origin SCID mice possess a genetic autosomal recessive mutation (SCID). Discovered in 1980 by Bosma in C.B-17/Icr mice at Fox Chase Cancer Center. SCID mice show a severe combined immunodeficiency affecting both B and T lymphocytes. They have normal NK ... more

Balb/C-nude

Origin Developed through crosses and back-crosses between BALB/cABom-nu and BALB/cAnNCrj at Charles River Laboratories Japan (CRLJ). Pedigreed pregnant females of CAnN.Cg-Foxn1nu/Crl were received from CRLJ in 1985. This mouse is inbred, and genetic monitoring results confirm it to be a BALB/c ... more

Nude mice

Origin The mutation occured in 1962, in a colony of albino outbred mice maintained at the Ruchill Hospital in Glasgow. In 1966, Flanagan gave the first detailed description of this mutant. It was not until 1986, however, that it was ... more

PGP

Origin In 1995, a subpopulation of CF-1™ mice with deficient expression of mdr1a P-glycoprotein (PGP) was identified by the department of Safety Assessment, Merck Research Laboratories, West Point, PA. Genotyping led to the identification of homozygous populations, mutant (-/-) and wild-type (+/+), ... more

OT II

Origin From the Walter and Eliza Hall Institute, Victoria, Australia, to Charles River France in 2002. These homozygous transgenic mice express the mouse alpha-chain and beta-chain T cell receptor that pairs witht the CD4 coreceptor and is specific for chicken ... more

OT I

Origin From the Walter and Eliza Hall Institute, Victoria, Australia, to Charles River France in 2002. These homozygous mice contain transgenic inserts for mouse Tcra-V2 and Tcrb-V5 genes. The transgenic T cell receptor was designed to recognize ovalbumin residues 257-264 in ... more

Ly5.1

Origin The strain was originally developed at the Sloan Kettering Institute where it was backcrossed on a non-specified C57BL/6 strain. The congenic strain C57BL/6-Ly5.1 carries the allele of the SJL mouse in the Ptprc gene locus: Ptprca or CD45.1 or Ly5.1. Charles ... more

The Pound Mouse

Origin This model was isolated from a C57BL/6NCrl colony in a Charles River Laboratories barrier facility in the United States in 2005. The mutation was mapped to a region within less than 2 cM of the leptin receptor on Chr ... more

NMRCF1

Origin The hybrid NMRCF1/Crl mouse is a result from a cross between a Crl:NMRI female and a JAXTM Mice Strain BALB/cByJ male. Coat ... more

CD2F1/Crl

Origin First generation (F1) progeny of a cross between female BALB/cAnNCrl and male DBA/2NCrl mice. Coat color Brown agouti Breeding ... more

CB6F1/Crl

Origin A cross between female BALB/c and male C57BL/6. Strain code 176 Coat color Agouti Research application Transplantation research, monoclonal antibody ... more

B6C3F1/Crl

Origin A cross between female C57BL/6 and male C3H. Contact us for further information. Strain code 031 Coat color Agouti (wild-type) Research application Safety and efficacy testing, transgenic/knockout model development, transplantation ... more

B6 Albino

Origin Received by NCI from Dr. Allan Bradley at Baylor College of Medicine in 2000. The B6 albino strain is a spontaneous albino mutant coisogenic C57BL/6 strain. The mice contain a mutation in the tyrosinase gene, and when homozygous for ... more

FVB

Origin Derived in 1935 from an outbred Swiss colony [N:GP(S)] at NIH. In the early 1970s, while being established as an inbred strain, sensitivity to Friend leukemia virus B strain was discovered. At this time inbreeding of this line for the Fv1b allele ... more

DBA/2NCrl

Origin Developed by C.C. Little in 1909 from stock segregating for coat color. Oldest of all the inbred strains of mice. In 1929-1930, crosses were made between sublines, and several new sublines were established, including the widely used sublines 1 ... more

CBA/Ca

Origin From a cross of a Bagg albino female and a DBA male by Strong in 1920. The CBA strain was selected for a low mammary tumour incidence. Transferred via The Jackson Laboratory to Haldane and Gruneberg in 1932. To Carter ... more

BL/6N

Origin Developed by C.C. Little in 1921, from a mating of Miss Abby Lathrop’s stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To The Jackson Laboratory in 1948 from Hall. To ... more

C3H/N

Origin From a cross of a Bagg albino female and a DBA male by Strong in 1920. A litter of 4 females and 2 males sent to Andervont in 1930, then to Heston at F35. To NIH in 1951 from ... more

Balb/cN

Origin H.J. Bagg developed the “Bagg albino” in 1913 from stock from an Ohio pet dealer. Inbred in 1923 by McDowell. To Snell in 1932 at F26, then to Andervont in 1935. To NIH in 1951 from Andervont at F72. ... more

129

Origin Developed by Dr. L.C. Stevens from The Jackson Laboratory.  During the 1970s, Dr. Stevens introduced this line to the Pasteur Institute of Paris in the laboratory of Dr. J.L. Guenet. To Iffa Credo in August 1996. To Charles River ... more

Black Swiss

Origin Developed at the NIH Genetic Resource by Dr. Carl Hansen. N:NIH Swiss outbred mice (albino) were crossed to C57BL/6N (black, non-agouti) mice to generate a hybrid black mouse that was heterozygous for the agouti locus. Through a series of ... more

SKH1 Hairless

Strain origin An uncharacterized non-pedigreed hairless strain of mice was acquired by Temple University from a small commercial supplier in New York City. To Charles River from the Skin and Cancer Hospital at Temple University in 1986. This mouse is euthymic and immunocompetent. Control No ... more

OF1

Strain origin In 1935, Carworth Farm began to breed a line of mice for vigor and productivity. Progenitors originating from a colony bred in Missouri were bought and the strain was named CF1 (Carworth Farm 1). This strain was introduced to Charles River ... more

MF1

Origin These albino mice, which were originally developed at Olac prior to 1970, came from a cross between the Laboratory Animal Centre A-strain mice (‘LACA’ - but formerly called CFW) and the CS1 from Scientific Products Farm (acquired by Charles ... more

CD – 1 IGS

Origin The original group of Swiss mice that served as progenitors of this stock consisted of two male and seven female albino mice derived from a non-inbred stock in the laboratory of Dr. de Coulon, Centre Anticancereux Romand, Lausanne, Switzerland. ... more

HSD11B1

Origin HSD11B1 mice were created by Pfizer, Inc. Transferred to Charles River under exclusive license in 2011. Strain code 519 HE, 520 HO, 521 WT Coat color White (albino) Research application Cortisone regulation Ordering information For further information or to place an order, please contact us at info@velaz.cz ... more