Inbred

129-E Mouse

NOTE: The E indicates that this animal’s health status meets our VAF/Elite™ profile. For additional information, please check out the VAF/Elite™ definition: http://www.criver.com/files/pdfs/rms/rm_rm_r_vaf_profiles.aspx Origin Developed by Dr. L.C. Stevens from The Jackson Laboratory. During the 1970s, Dr. Stevens introduced this line to ... more

11BHSD2 Mouse

Origin The 11BHSD2 mouse was produced by injection of a construct, containing 11β-HSD2 cDNA isolated from mouse kidney and cloned into plasmid Clone 26 to recruit the 5.4 kb mouse α–myosin heavy chain (α-MHC) promoter, into pronuclei of C57BL/6 embryos. ... more

B6 Albino

Origin Received by NCI from Dr. Allan Bradley at Baylor College of Medicine in 2000. The B6 albino strain is a spontaneous albino mutant coisogenic C57BL/6 strain. The mice contain a mutation in the tyrosinase gene, and when homozygous for ... more

FVB

Origin Derived in 1935 from an outbred Swiss colony [N:GP(S)] at NIH. In the early 1970s, while being established as an inbred strain, sensitivity to Friend leukemia virus B strain was discovered. At this time inbreeding of this line for the Fv1b allele ... more

DBA/2NCrl

Origin Developed by C.C. Little in 1909 from stock segregating for coat color. Oldest of all the inbred strains of mice. In 1929-1930, crosses were made between sublines, and several new sublines were established, including the widely used sublines 1 ... more

CBA/Ca

Origin From a cross of a Bagg albino female and a DBA male by Strong in 1920. The CBA strain was selected for a low mammary tumour incidence. Transferred via The Jackson Laboratory to Haldane and Gruneberg in 1932. To Carter ... more

BL/6N

Origin Developed by C.C. Little in 1921, from a mating of Miss Abby Lathrop’s stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To The Jackson Laboratory in 1948 from Hall. To ... more

C3H/N

Origin From a cross of a Bagg albino female and a DBA male by Strong in 1920. A litter of 4 females and 2 males sent to Andervont in 1930, then to Heston at F35. To NIH in 1951 from ... more

Balb/cN

Origin H.J. Bagg developed the “Bagg albino” in 1913 from stock from an Ohio pet dealer. Inbred in 1923 by McDowell. To Snell in 1932 at F26, then to Andervont in 1935. To NIH in 1951 from Andervont at F72. ... more

129

Origin Developed by Dr. L.C. Stevens from The Jackson Laboratory.  During the 1970s, Dr. Stevens introduced this line to the Pasteur Institute of Paris in the laboratory of Dr. J.L. Guenet. To Iffa Credo in August 1996. To Charles River ... more